Ankit Rochani

Dr. Rochani focuses on creating semisolid dosage forms (hydrogels, emulsions, creams, and lotions) and nanoformulations (polymeric micelles, liposomes, niosomes, and metallic/organometallic nanoparticles). His academic research is focused on understanding the moldable chemistry of sustainable green biomaterials for developing biomimetic personalized dosage forms. His expertise lies in HPLC, and LCMS or MS/MS-based method development, particularly for large and small molecular investigations. His work supports clinical pharmacies and compounding facilities by generating HPLC-based stability data for various solids and liquid dosage forms. Collaborating closely with formulation experts, Dr. Rochani has provided robust HPLC-based assays to study dissolution and drug release kinetics for various dosage forms and implantable devices.

Publications

• Aspirin pharmacokinetics and pharmacodynamics through gestation. Am J Obstet Gynecol.  2023 Dec 23. Co-authored with RC Boelig, G Kaushal, S McKenzie, and WK Kraft. S0002-9378(23)02183-X.
• Tumoral oxygenation and biodistribution of Lonidamine oxygen microbubbles following localized ultrasound-triggered delivery. Int J Pharm. Sep 2022. Co-authored with Q Lacerda, B Oeffinger, JB Liu, C Wessner, A Tahmasebi, H Falateh, P Lee, D Leeper, F Frosberg, J Curry, S Keith, P Kane, G Kaushal, M Wheatley, J Eisenbrey. 625: 122072.
• Stability-indicating HPLC method to determine the stability of extemporaneously prepared vancomycin oral solution cups. Am J Health Syst Pharm. Jan 2021. Co-authored with V Nguyen, R Becker, and G Kaushal. Jul 6; zxab259.
• Stability-indicating LC-MS method for determination of stability of extemporaneously compounded buprenorphine oral syringes for neonatal abstinence syndrome. J Pediatr Pharmacol Ther. May 2021. Co-authored with V Nuygen, R Becker, W Kraft, and G Kaushal; 26(4):395-404.
• Heat Shock Protein 90 (Hsp90)-Inhibitor-Luminespib-Loaded-Protein-Based Nanoformulation for Cancer Therapy. Polymers. Aug 2020. Co-authored with S Balasubramanian, AR Girija, T Maekawa, G Kaushal, and DS Kumar; 12(8), 1798.
• Simultaneous Quantitative LC-MS Method of Ketamine, Midazolam and their Metabolites for its Application in Patients on Extracorporeal Membrane Oxygenation (ECMO) Therapy, J Pharm Biomed Anal. 2020 Jan. Co-authored with E Lam, J Tanjuakio, H Hirose, W Kraft, and G Kaushal; 178:112947.

Magazine Articles

• Sustainable Green Biomaterials in Biomimetic Drug Delivery. AAPS News Magazine. Feb 2024. Co-authored with M Quinn, S Georgeadis, M Said, S Narh, A Bajaj.
• What do we know about albumin formulations? Pharmafocusasia Magazine. April 2024. Co-authored with L Condon, M Suthar, S Woytowicz, G Kaushal. 

Published Posters

• Implementation of Innovative Lab-Based Compounding Courses to an Online PharmD Pathway. American Journal of Pharmaceutical Education; 87 (8). August 2023. Co-authored with L Chablani, V Dave, P Bhatt: https://www.sciencedirect.com/science/article/pii/S000294592300267X 
• Azithromycin Dose and PPROM Treatment (ADAPT): a randomized controlled Phase I trial. American Journal of Obstetrics & Gynecology. Jan 2024. Co-authored with RC Boelig, G Kaushal, W Kraft, 230 (1), S219: https://www.sciencedirect.com/science/article/pii/S000293782301222X?via%3Dihub 
• Application of population modeling to characterize the effect of pregnancy on aspirin pharmacokinetics. American Journal of Obstetrics & Gynecology. Feb 2023. Co-authored with M Abdelmageed, N Moraes, S Schmidt, V Vozmediano, W Kraft, R Boelig, 228 (1), S180: https://www.ajog.org/article/S0002-9378(22)01225-X/fulltext

Poster/ Oral Presentations

• Albumin Hydrogel Formulation and Potential Biomedical Applications. Short Topic Oral-Presentation (20min): AAPS-Northeast Regional Discussion Group (NERDG), Connecticut, Groton, CT. Co-authored with L. Condon, R. Hailstone, S. Woytowicz, T. Camenisch, G. Kaushal. Short Topic Presentation Award
• Personalized Nano Drug Delivery Strategies Using Smart and Green Biomaterials. Recent Advances in Pharmaceutical Sciences Conference, (2021) India.
• Incubation Method for Loading Lonidamine in Oxygen Microbubbles for Targeted Drug Delivery. Journal of Ultrasound Medicine, 2020 Volume 39, Issue S1. Co-authored with Q Lacerda, B Oeffinger, R Patel, M Wheatley, D Leeper, F Forsberg, P O’Kane, G Kaushal, J Eisenbrey: https://ieeexplore.ieee.org/document/9251788 
• LC-MS Method Development for Quantitation of Midazolam and Ketamine and their Clinically Relevant Metabolites a Patient of ECMO Therapy. Postdoctoral Research Symposium, Thomas Jefferson University, (2019) Philadelphia.

Book Chapters

• Theranostics: A New Holistic Approach in Nanomedicine, Chapter 14 of book Bio Nanotechnology in Cancer: Diagnosis and Therapy, Publisher: Jenny Stanford Publishing Pte. Ltd., Penthouse Level, Suntec Tower 3, 8 Temasek Boulevard, Singapore, 2022. Editor: D. Sakthi Kumar and Aswathy R.G. eISBN: 9780429422911. Co-authored with S. Raveendran. 
• Sustainable Green Polymeric Nano Constructs for Active and Passive Cancer Therapeutics, Chapter 7 of book Handbook of Materials for Nanomedicine (Polymeric Nanomaterials), Published by CRS Press, Taylor Francis group, 2020. Editor: Vladimir Torchilin. ISBN: 9789814800921. Co-authored with S. Raveendran and DS Kumar. 

 Research Awards

• 2014-2017: Japanese Govt Scholarship (MEXT)
• 2014-2017: Inoue Enryo Grant Award, Toyo University.
• 2022-2023: Scholarly Innovation Grant (SIG), St John Fisher University
• 2023-2024: Faculty Innovative Development Grant (FIDG), St. John Fisher University
• 2023-2024: Faculty Research Award Program (FRAP), St. John Fisher University

Publications on Google Scholar

Fisher Digital Publications